CORE-ABR
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Pathogen

Streptococcus pyogenes

Group A streptococcus — a cause of cellulitis, erysipelas and necrotizing soft-tissue infection.

Also: group A strep, GAS

Gram-positive bacteriaUTI panelWound panelGraded on the antibiogram

How CORE-ABR grades it

S. pyogenes remains reliably susceptible to penicillin, so beta-lactams stay first line. Macrolide and clindamycin activity depend on erm genes.

What the report shows for Streptococcus pyogenes

  • Detected or not detected, with Ct, limit of detection and cycles above LOD — see PCR reporting.
  • A short pathogen summary, including colonizer likelihood where it applies.
  • A graded column on the antibiogram, and therapy options by scenario on the P.A.C.T. report.
  • When not detected, it is still listed among targets tested.

Resistance genes CORE-ABR applies

When detected, each of these genes is applied to Streptococcus pyogenes only for the agents its mechanism defeats.

ermB / ermCMLSb resistance7 organisms on paneltetB / tetMTetracycline resistance9 organisms on panel

Tagged

Decision support only. The treating clinician decides. Molecular genotype does not replace phenotypic susceptibility testing, culture, or public-health reporting. Absence of a detected resistance gene does not establish susceptibility. Organism targets vary by panel; CORE-ABR is configured to the assay each laboratory runs.