CORE-ABR
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Pathogen

Enterobacter aerogenes / cloacae

Enterobacterales with chromosomal AmpC. E. aerogenes has been renamed Klebsiella aerogenes; many panels still report the older name.

Also: Klebsiella aerogenes, Enterobacter cloacae complex

Gram-negative bacteriaUTI panelWound panelSTI panelGraded on the antibiogram

How CORE-ABR grades it

Intrinsic resistance applied: ampicillin, amoxicillin-clavulanate, ampicillin-sulbactam, first-generation cephalosporins and cephamycins. As with other AmpC producers, third-generation cephalosporins are treated with caution for serious infection.

What the report shows for Enterobacter aerogenes / cloacae

  • Detected or not detected, with Ct, limit of detection and cycles above LOD — see PCR reporting.
  • A short pathogen summary, including colonizer likelihood where it applies.
  • A graded column on the antibiogram, and therapy options by scenario on the P.A.C.T. report.
  • When not detected, it is still listed among targets tested.

Resistance genes CORE-ABR applies

When detected, each of these genes is applied to Enterobacter aerogenes / cloacae only for the agents its mechanism defeats.

Class C beta-lactamase (AmpC)AmpC cephalosporinase production5 organisms on panelClass A beta-lactamase (CTX-M)Extended-spectrum beta-lactamase (ESBL) production6 organisms on panelClass A beta-lactamase (KPC / SHV)Carbapenemase (KPC) or ESBL (SHV variants) production5 organisms on panelqnrA / qnrBPlasmid-mediated quinolone resistance7 organisms on paneldfrA1 / dfrA5Trimethoprim resistance6 organisms on panelsul1 / sul2Sulfonamide resistance6 organisms on panel

Tagged

Decision support only. The treating clinician decides. Molecular genotype does not replace phenotypic susceptibility testing, culture, or public-health reporting. Absence of a detected resistance gene does not establish susceptibility. Organism targets vary by panel; CORE-ABR is configured to the assay each laboratory runs.